Praxis Biology (5236)
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Praxis® is a registered trademark of ETS, which is not affiliated with and does not endorse Test Treasure Publication or TTP Prep.
10 sample questions for the Praxis Biology (5236), with the correct answer and an explanation for each. No account needed. Try each one before you open the answer.
Sections covered on the exam: Nature and Impact of Science and Engineering, Cell Biology: Cell Structure and Function, Genetics and Evolution, Diversity of Life and Organismal Biology, Ecology: Organisms and Environments.
Question 1 · Nature and Impact of Science and Engineering
Answer: B. Explain that a theory is a well-tested explanation that unifies many lines of evidence.
In science, a theory is a broad, well-substantiated explanation supported by many independent lines of evidence (fossils, comparative anatomy, molecular data, observed selection), not a guess. Telling students a theory "becomes a law" reinforces a common misconception: laws describe patterns, while theories explain them, so one never graduates into the other. Acceptance rests on evidence, not on a vote.
Question 2 · Cell Biology: Cell Structure and Function
Answer: D. Tight junctions
Tight junctions seal adjacent plasma membranes and block leakage of fluid through the spaces between epithelial cells, so their loss lets dye seep between cells. Firm adhesion shows desmosomes are intact, and continued cytoplasm-to-cytoplasm passage shows gap junctions still work. Adherens junctions, like desmosomes, anchor cells to one another rather than sealing the spaces between them.
Question 3 · Genetics and Evolution
Answer: A. 9/32
Treat each gene separately and multiply: Aa × Aa gives 3/4 A_, Bb × Bb gives 3/4 B_, and Cc × cc gives 1/2 C_, so 3/4 × 3/4 × 1/2 = 9/32. The value 27/64 comes from wrongly treating the third gene as Cc × Cc, and 9/64 comes from using 1/4 instead of 1/2 for the Cc × cc cross.
Question 4 · Genetics and Evolution
Answer: C. Many unrelated marine and land groups vanish in one geologically brief interval.
A mass extinction is defined by the loss of a large fraction of species across many unrelated taxa and environments in a short span of geologic time. The turnover of a single genus and a slow decline in one habitat fit normal background extinction, and a change in body size says nothing about how many lineages were lost.
Question 5 · Diversity of Life and Organismal Biology
Answer: C. 14 and 21
One sperm (n = 7) fertilizes the egg (n = 7), forming a 2n = 14 zygote that develops into the embryo. The second sperm fuses with the two polar nuclei of the central cell (n + n), forming triploid endosperm with 3n = 21. Answering 14 for the endosperm ignores the second polar nucleus.
Question 6 · Nature and Impact of Science and Engineering
Answer: C. More pill bugs will settle on the moist side of a choice chamber than the dry side.
A good hypothesis is testable and falsifiable : it names a measurable outcome (number of pill bugs on each side) and a manipulated variable (moisture). "Happier" cannot be measured directly, "designed" invokes a purpose that cannot be tested experimentally, and ecosystem importance is a general statement rather than a prediction a classroom experiment can check.
Question 7 · Cell Biology: Cell Structure and Function
| Cell | Rough ER | Smooth ER | Mitochondria | Lysosomes |
|---|---|---|---|---|
| W | 22 | 2 | 8 | 1 |
| X | 3 | 35 | 12 | 1 |
| Y | 2 | 4 | 40 | 1 |
| Z | 4 | 3 | 9 | 15 |
Answer: C. Cell X
Steroid hormones are lipids synthesized largely by enzymes of the smooth ER, so a steroid-secreting cell has an unusually extensive smooth ER, as in cell X (35%). Cell W, with abundant rough ER, fits a protein-secreting cell such as a pancreatic acinar cell; cell Y, rich in mitochondria, fits a muscle cell; cell Z, rich in lysosomes, fits a phagocyte such as a macrophage.
Question 8 · Genetics and Evolution
Answer: B. A man with type AB blood
The ABO gene has three alleles (Iᴬ and Iᴮ are codominant, and both are dominant to i); a type O child is ii, so she received an i allele from each parent. A type AB man is IᴬIᴮ and carries no i allele, so he cannot be the father. Men with type A or B could be heterozygous (Iᴬi or Iᴮi), and a type O man is ii.
Question 9 · Genetics and Evolution
| Interval | Mammal families known | Body mass of largest mammals (kg) |
|---|---|---|
| 10 million years before the boundary | 25 | ≈ 10 |
| At the extinction boundary | 18 | ≈ 5 |
| 10 million years after the boundary | 78 | ≈ 500 |
Answer: B. Extinctions freed ecological niches, and surviving mammals underwent adaptive radiation
Mammal families fell slightly at the boundary but more than quadrupled (18 → 78) within 10 million years, and maximum body size rose about a hundredfold as lineages diversified into roles previously filled by dinosaurs. Rapid diversification into newly vacant niches after a mass extinction is adaptive radiation . Mammals had coexisted with dinosaurs for over 100 million years without displacing them, and mutations arise randomly rather than being produced to fill niches.
Question 10 · Diversity of Life and Organismal Biology
Answer: C. 1.5 m
Stems lengthen only at apical meristems at the shoot tips, so tissue already formed at 1.5 m does not move upward; the trunk thickens through the vascular cambium, a lateral meristem, but does not elongate. Answering 4.5 m assumes the whole trunk stretched uniformly (3 m → 9 m is a tripling), and 7.5 m assumes the nail rose by the full 6 m of growth.
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